Xanax (alprazolam)
Other names: Aprazolam Intensol
About Xanax | Aprazolam Intensol
Xanax (alprazolam) is an anti-panic and anti-anxiety medication.
Xanax is in the group of drugs known as benzodiazepines, a class
of antidepressants, anti-panic agents, and muscle relaxants. Xanax
is only available by prescription.
Xanax is usually used as a short term treatment for major
anxiety and certain phobias, but is not considered necessary
to relieve everyday stress or anxiety.
Xanax has been prescribed as a treatment for:
- Anxiety disorder characterized by unrealistic fears and excessive
worries.
- Panic Disorder, sometimes accompanied by fear of open spaces
(agoraphobia).
- Also for the temporary symptoms of alcohol withdrawal, depression,
fear of strangers, irritable bowel, and premenstrual syndrome.
Dosage varies.
- Xanax may be prescribed in low doses to treat fibromyalgia.
Store Xanax away from light and heat, use regularly for best
results.
Xanax Side Effects
Xanax side effects are usually temporary, and fade with continued
treatment. Higher dosage also increases the risk of side effects.
Operating automobiles or heavy machinery is not recommended while
taking Xanax. Be aware of how this medication affects you before
attempting any potentially dangerous activities.
Common Xanax side effects: drowsiness, fatigue, light-headedness,
or speech problems.
Less common Xanax side effects: abdominal cramps, constipation,
dry mouth, hyperventilation, blurred vision, nausea, chest pain,
change in sex drive, confusion, headache, change in appetite, insomnia,
unusual dreams, change in salivation, low blood pressure, racing
heartbeat, fainting, nasal congestion, difficulty urinating, sweating,
weight change, skin irritation, twitching or tremors, nervous or
anxious state, sun sensitivity, respiratory infection, memory impairment,
menstrual difficulties, and loss of coordination. Speak to your
doctor about any of these effects; your dosage may need to be adjusted
or treatment discontinued.
Rare Xanax side effects: difficulty concentrating, slurred
or unusual speech, double vision, fear, altered sense of taste,
lack of inhibition, muscle cramps or spasms, urination problems,
tingling, incontinence, warmth, weakness, change in muscle tone,
or yellow eyes and skin. Speak to your doctor if you experience
any of these effects; your treatment may need to be discontinued.
Xanax treatment should be discontinued if any of the following
occur: hyperexcitement, muscle spasm, anxiety, hallucinations,
rage or other hostile behavior, tremors, insomnia, sleeping difficulties
or overstimulation.
Cautions: Xanax has been known to interact undesirably with certain medical conditions. Tell your doctor if you have, or have a history of, any of the following conditions:
- Alcohol or drug abuse - may increase likelihood of Xanax dependence
- Allergic reaction to Xanax, or other benzodiazepine. Always
tell your doctor about any allergies before starting a medication.
- Borderline personality disorder or a history of violent behavior.
- Brain disease - may increase likelihood of side effects from
Xanax
- Breathing difficulties such as asthma, bronchitis, emphysema,
or any other chronic lung disease - Xanax may worsen this condition.
- Difficulty swallowing - This condition may become more pronounced
in children.
- Epilepsy or seizures - Abruptly starting or stopping treatment
with Xanax may increase seizures. Although Xanax can be used as
an aid to anti-tremor therapy, it should be used cautiously and
strictly according to a doctor's instructions in these cases.
- Glaucoma - Xanax should not be prescribed to patients with acute
narrow-angle glaucoma. Patients receiving treatment for open angle
glaucoma should consult their doctor, as Xanax may be an acceptable
treatment for them.
- Hyperactivity
- Kidney or liver problems - In isolated cases, Xanax has been
reported to cause jaundice. If you experience yellowing of the
skin or eyes, seek medical treatment immediately. More Xanax may
end up in your bloodstream if you have a pre-existing kidney or
liver condition, increasing the likelihood of side effects.
- Major Depression
- Myasthenia gravis - This autoimmune disorder characterized by
muscle weakness may be aggravated by Xanax treatment.
- Porphyria - Xanax (alprazolam) is listed as an unsafe drug for
porphyria, an enzyme deficiency that can cause fragile skin that
is sensitive to sunlight, digestive difficulties, anxiety, and
reddish-brown urine.
- Psychosis or other serious mental illness - Xanax has not proved
to be an effective treatment for these conditions, and is not
recommended.
- Sleep apnea (temporary suspension of breathing during sleep)
- Xanax may worsen this condition. Individuals with sleep apnea
should not generally use sedatives as sleep aids. (See Sleep Disorders)
Dependence: Xanax has been known to be habit-forming. Withdrawal symptoms may occur if treatment is discontinued abruptly. Follow your doctor's advice about how much, and how often, you should take Xanax. If you are considering stopping Xanax treatment, ask your doctor how to safely decrease and then stop Xanax.
Xanax Interactions
Xanax slows the central nervous system, and should be taken with
care with medications that do the same thing. When Xanax is taken
with certain other medications, the rate of side effects may increase,
and the action of either medication may be increased or altered.
Certain medications can cause an undesirable build-up of Xanax in
the body. Ask your doctor's advice about combining Xanax with any
of the following:
- Alcohol - Xanax should not be mixed with alcohol, it increases
the risk of overdose and fatal toxicity.
- Agenerase (amprenavir)
- Any medication which may cause drowsiness
- Antibiotics (esp. macrolide antibiotics) like azithromycin,
biaxin, clarythromycin, or erythromycin
- Antihistamines like Tavist or Benadryl
- Adalat, Procardia (nifedipine)
- Antabuse (disulfiram)
- Antiseizure medication like Cerebyx (fosphenytoin), Dilantin
(phenytoin), or Tegretol (carbamazepine).
- Benzodiazepines of any other type, such as Valium
(diazepam), Halcion (triazolam), Restoril (temazepam), Librium
(chlordiazepoxide), Tranxene-SD (clorazepate), Paxipam (halazepam),
ProSom (estazolam), Klonopin
(clonazepam)
- BuSpar (buspirone) - Can result in oversedation.
- Cardene (nicardipine)
- Cordarone (amiodarone)
- Desyrel (trazodone) - Risk of additive
CNS depression.
- Diflucan (fluconazole)
- Ergotamine derivatives
- Grapefruit juice
- Kava kava - Do not take this herb while taking Xanax.
- Lanoxin (digoxin)
- MAO inhibitors such as the antidepressants Nardil or Parnate.
- Narcotic analgesics of any kind, like Darvon (propoxyphene),
Darvocet (propoxyphene, acetaminophen), Demerol
(meperidine), Codeine, Percocet
(oxycodone, acetaminophen), Vicodin
(hydrocodone, acetaminophen), Vicoprofen
(hydrocodone and ibuprofen) or OxyContin
(oxycodone) may accelerate central nervous system or respiratory
depression when taken with Xanax. Also, Xanax may decrease the
effectiveness of these medications as pain relievers.
- Norflex (orphenadrine) - Risk of oversedation.
- Neoral, Sandimmune (cyclosporine)
- Nicotine - Heavy smoking may reduce the effectiveness of your
treatment.
- Nizoral (ketoconazole) - Xanax should not be mixed with this
antifungal medication.
- Oral contraceptives - May increase the effects of Xanax.
- Prilosec (omeprazole) - May increase the effects of Xanax.
- Rescriptor (delavirdine)
- Rifamate (isoniazid), Rifater (rifampin), or Mycobutin (rifabutin)
- Sedatives like Fioricet
(butalbital, acetaminophen, and caffeine), Fiorinal
(butalbital, aspirin, and caffeine), Phenobarbitol, Seconal, or
other barbiturates
- Selective serotonin reuptake inhibitors (SSRIs) like Celexa
(citalopram), Paxil (paroxetine),
Prozac (fluoxetine), Luvox (fluvoxamine), or Zoloft (sertraline).
- Serzone (nefazodone)
- Skeletal muscle relaxants such as Flexeril
(cyclobenzaprine), Skelaxin (metaxalone), Soma (carisoprodol),
or Robaxin (methocarbamol)
may cause oversedation in combination with this medication.
- Sleep medication like Ambien
(zolpidem), Sonata (zaleplon),
or over the counter sleeping pills should be used with Xanax only
as, and if, advised by your doctor.
- Sporanox (itraconazole) - Xanax should not be mixed with this
antifungal medication.
- Street drugs - Marijuana may increase sedative effects from
Xanax.
- St. John's Wort - Do not take this herb while taking Xanax.
- Tagamet (cimetidine)
- Tranquilizers such as Haldol (haloperidol), Mellaril (thioridazine),
or Thorazine (chlorpromazine) may cause oversedation.
- Tricyclic antidepressants such as Elavil
(amitriptyline), Asendin (amoxapine), Anafranil (clomipramine),
Pertofrane or Norpramin (desipramine), Sinequan
(doxepin), Tofranil (imipramine), Aventyl or Pamelor (nortriptyline),
Vivactil (protriptyline), and Surmontil (trimipramine), may increase
the risk of side effects from Xanax.
- Valerian - Do not take this herb while taking Xanax.
Talk with your doctor if you are considering mixing an antidepressant
and anxiety medication like Xanax with any other antidepressant,
or any medication that may cause drowsiness. Anxiety medication
can have increased, unexpected, or severe side effects when mixed
with other medications that affect the central nervous system. Stimulants
of any type may blunt the effectiveness of Xanax.
Xanax Dosages
Xanax comes in doses of .25 mg (white oval tablet), .5 mg (pink
oval tablet), 1 mg (blue oval tablet), and 2mg (white oblong tablet,
scored). The usual starting dose is .25-.5 mg, 3-4 times per day,
up to a maximum of 4-6 mg per day, divided among several doses.
Xanax Directions
Xanax should be taken exactly as your doctor recommends.
Don't take more or less than prescribed, and don't double
your doses if you should miss one. Take your doctor's advice
about how quickly or slowly to ease off Xanax treatment if
you plan to stop taking it. Xanax should not be started or
stopped abruptly, as it strongly increases the likelihood
of side effects. If you have a convulsive disorder, or experience
severe muscle spasming, abruptly stopping or starting Xanax
could increase these effects.
Avoid grapefruit juice while using Xanax, may alter the effectiveness
of your treatment.
Symptoms of overdose or severe reaction can include confusion,
poor coordination, sleepiness, shuffling walk, persistent
fine tremor or inability to sit still, fever, difficulty breathing
or swallowing, severe skin rash, yellowing of the skin or
eyes, irregular heartbeat, or coma. Seek medical treatment
immediately if you suspect an overdose, contact emergency
services if an individual begins to lose consciousness or
stops breathing.
Keep this medication in the container it came in, tightly
closed, and out of reach of children. Store it at room temperature
and away from excess heat and moisture (not in the bathroom).
Throw away any medication that is outdated or no longer needed,
making sure that children can't reach it even after disposal.
This medication not suitable for pregnant or breastfeeding
women, and has not been tested in children. Seniors advised
to used the smallest possible dose, and to be alert for undesirable
side effects or sign of overdose, as the medication may build
to excess in the body.
Xanax is a trademark of Pharmacia & Upjohn
This document is provided for information only. It is not a substitute for consultation with a physician, either to diagnose symptoms or prescribe treatment. The dosages mentioned are general manufacturers guidelines only, please follow the directions of your doctor or pharmacist exactly when taking medication. Dosage recommendations for children and seniors may vary significantly from standard dosages, and pregnant women should always speak to their OB/GYN before taking any medication. We have made every effort to ensure that the information presented is accurate, but only your doctor can say if a medication, or drug combination, is safe for you. Information intended for US residents only.
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